SFG Publications
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC.
Cell. 2018 Oct 30. pii: S0092-8674(18)31309-6. doi: 10.1016/j.cell.2018.10.001. [Epub ahead of print]
Public resources aid diabetes gene discovery.
D.L. Cousminer and S.F.A. Grant
Nature Genetics Epub ahead of print, October 2018.
First Genome Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes.
D.L. Cousminer*, E. Ahlqvist*, R. Mishra*, M.K. Andersen*, A. Chesi, M.I. Hawa, A. Davis, K.M. Hodge, J.P. Bradfield, K. Zhou, V.C. Guy, M. Åkerlund, M. Wod, L.G. Fritsche, H. Vestergaard, J. Snyder, K. Højlund, A. Linneberg, A. Käräjämäki, I. Brandslund, C.E. Kim, D. Witte, E. Pettersen Sørgjerd, D.J. Brillon, O. Pedersen, H. Beck-Nielsen, N. Grarup, R.E. Pratley, M.R. Rickels, A. Vella, F. Ovalle, O. Melander, R.I. Harris, S. Varvel, V.E.R. Grill, Bone Mineral Density in Childhood Study, H. Hakonarson, P. Froguel, J.T. Lonsdale, D. Mauricio, N.C. Schloot, K. Khunti, C.J. Greenbaum, B.O. Åsvold, K.B. Yderstræde, E.R. Pearson, S. Schwartz, B.F. Voight, T. Hansen, T. Tuomi, B.O. Boehm*, L. Groop*, R.D. Leslie* and S.F.A. Grant*
Diabetes Care Epub ahead of print, September 2018 Notes: *equal contribution.
Leveraging epigenomics and contactomics data to investigate SNP pairs in GWAS
Elisabetta Manduchi, Scott M. Williams, Alessandra Chesi, Matthew E. Johnson, Andrew D. Wells, Struan F.A. Grant, Jason H. Moore
Hum Genet. 2018 May; 137(5): 413–425. Published online 2018 May 24. doi: 10.1007/s00439-018-1893-0
Leveraging Putative Enhancer-Promoter Interactions to Investigate Two-Way Epistasis in Type 2 Diabetes GWAS
Manduchi E, Chesi A, Hall MA, Grant SFA, Moore JH.
Pac Symp Biocomput. 2018;23:548-558.
The Loss of TET2 Promotes CD8+ T Cell Memory Differentiation
Carty SA, Gohil M, Banks LB, Cotton RM, Johnson ME, Stelekati E, Wells AD, Wherry EJ, Koretzky GA, Jordan MS.
J Immunol. 2018 Jan 1;200(1):82-91.
Antagonism of B Cell Enhancer Networks by STAT5 Drives Leukemia and Poor Patient Survival
Katerndahl CDS, Heltemes-Harris LM, Willette MJL, Henzler CM, Frietze S, Yang R, Schjerven H, Silverstein KAT, Ramsey LB, Hubbard G, Wells AD, Kuiper RP, Scheijen B, van Leeuwen FN, M¸schen M, Kornblau SM, Farrar MA.
Nat Immunol. 2017 Jun;18(6):694-704.
Ndfip1 Restricts mTORC1 Signaling and Glycolysis in Regulatory T Cells to Prevent Autoinflammatory Disease
Layman AAK, Deng G, O'Leary CE, Tadros S, Thomas RM, Dybas JM, Moser EK, Wells AD, Doliba NM, Oliver PM.
Nat Commun. 2017 Jun 5;8:15677.
A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression
Gallagher MD, Posavi M, Huang P, Unger TL, Berlyand Y, Gruenewald AL, Chesi A, Manduchi E, Wells AD, Grant SFA, Blobel GA, Brown CD, Chen-Plotkin AS.
Am J Hum Genet. 2017 Nov 2;101(5):643-663.
Implicating Candidate Genes at GWAS Signals by Leveraging Topologically Associating Domains
Way GP, Youngstrom DW, Hankenson KD, Greene CS, Grant SF.
Eur J Hum Genet. 2017 Nov;25(11):1286-1289.