Spatial & Functional
Genomics Affinity Group

SFG Grants

Decoding Methylation Mediated Epigenomic Contributions to Male Osteoporosis

PI: H.W. Deng
09/01/2006 to 08/31/2021

R01 AR069055

Role: Role: Co-Investigator (S. Grant)

Cyclin-dependent Kinases: Novel Switches in Anergy and Targets for Tolerance

PI: A. Wells
12/01/2015 to 11/30/2020

R01 AI054643-12

The major goal of this project is to determine the mechanisms by which CDK influence T cell memory vs. tolerance, and to test these enzymes as therapeutic targets in transplantation models.

Regulation of Skeletal Growth by Nuclear Retinoid Receptors

PI: M. Iwamoto
12/01/2008 to 08/31/2020

R01 AR056837

Role: Co-Investigator (S. Grant)

Genome Wide Association Study for Childhood Obesity

PI: S. Grant
07/15/2008 to 04/30/2020

R01 HD056465

The Myc-Mir-17-92 Axis in Colorectal Cancers

PI: A. Thomas-Tikhonenko
04/01/2015 to 03/31/2020

R01 CA196299

Role: Co-Investigator (S. Grant)

Genome Wide Association Study of Latent Autoimmune Diabetes in Adults

PI: S. Grant
07/01/2011 to 03/31/2020

R01 DK085212

TCF7L2, ACSL5 and Lipid Mediators in CF-Related Diabetes

CF Foundation
PI: R. Rubenstein
10/01/2016 to 09/30/2019


Role: Co-Investigator (S. Grant)

Variant to Gene Mapping for Type 2 Diabetes

PI: S. Grant
07/01/2016 to 06/30/2019

R21 HD089824

Exploiting Metabolic Vulnerabilities of CD4+ T Cell Subsets to Control Inflammation

PI: J. Rathmell
05/01/2015 to 04/30/2019

R01 DK100901

The major goal of this project is to determine the role of glucose and related metabolic pathways in regulating CD4+ T cell function.

Intergenic cis-Regulatory Elements in the Control of IL-2 and IL-21

PI: A. Wells
01/01/2014 to 11/30/2017

R21 AI110179-01

Role: Collaborator

The major goal of this project is to identify distal enhancer elements that regulate transcription of the IL-2 and IL-21 genes using ChIP and 3-dimensional chromosome capture approaches.