SFG Grants
Promoter interactome-aided mapping of unexplored CVID genetic landscapes
NIAID
PI: N. Romberg
07/16/2019 to 06/30/2024
Role: Co-Investigator
Functional Mechanisms of T1D Risk Variants and their Target Genes using 3D Epigenomics and Single Cell Approaches
NIDDK
PI: S. Grant, S. Rich, A. Wells
08/01/2019 to 05/31/2023
Network-based algorithms for drug discovery from genetic associations
NHGRI
PI: C Greene
06/12/2018 to 04/30/2023
Role: Co-Investigator
Treating Chronic Viral Infection by Epigenetic Reprogramming of Exhausted CD8 T Cells
PI: Shen
09/01/2017 to 08/31/2022
Role: Co-Investigator
The major goal of this project is to study how pharmacologic histone deacetylase inhibitors reprogram exhausted CD8 T cells at the epigenomic, transcriptional, and function level. These studies do not overlap with any of the other listed projects.
Epigenetic Imprinting of Follicular Helper T Cell Fate and Function in Lupus
NIH/NIAID
PI: Laufer
09/01/2017 to 08/31/2022
Role: Co-Investigator
The major goal of this project is to establish the epigenetic mechanisms involved in the Tfh cell fate decision, and whether these processes are dysregulated in individuals genetically susceptible to lupus. These studies do not overlap with any of the other listed projects.
Elucidation of Genetic Effects on Sleep and Circadian Traits
NHLBI
PI: P. Gehrman, S. Grant, A. Keene
09/01/2018 to 06/30/2022
Integrating GWAS of Sleep and Circadian Traits with functional follow-up efforts
Variant to Gene Mapping for Alzheimer's Disease
NIA
PI: S. Grant
09/15/2017 to 06/30/2022
Decoding Methylation Mediated Epigenomic Contributions to Male Osteoporosis
NIAMS
PI: H.W. Deng
09/01/2006 to 08/31/2021
Role: Role: Co-Investigator (S. Grant)
Cyclin-dependent Kinases: Novel Switches in Anergy and Targets for Tolerance
NIH/NIAID
PI: A. Wells
12/01/2015 to 11/30/2020
The major goal of this project is to determine the mechanisms by which CDK influence T cell memory vs. tolerance, and to test these enzymes as therapeutic targets in transplantation models.
Regulation of Skeletal Growth by Nuclear Retinoid Receptors
NIH/NIAMS
PI: M. Iwamoto
12/01/2008 to 08/31/2020
Role: Co-Investigator (S. Grant)